Textbook of Arterial Stiffness and Pulsatile Hemodynamics in Health and Disease, Two Volume Set covers the principles, physiology, biologic pathways, clinical implications and therapeutics surrounding arterial stiffness and pulsatile hemodynamics, along with a thorough overview of the field. The book presents complex engineering concepts in a way that those in science and medicine can more easily understand. It includes detailed illustrations. Additionally, it presents advanced bioengineering concepts in boxes for readers who wants more in-depth biophysical knowledge. This is a must-have reference for students, researchers and clinicians interested in learning more about this field.

Review

Provides a comprehensive review of the role of arterial stiffness and pulsatile hemodynamics in health and human disease

Contents

۱. Basic principles that determine relationships between pulsatile hemodynamic phenomena and function of elastic v
۲. Measurements of arterial pressure and flow in vrvo
۳. Essential principles of pulsatile pressure-flow relations in the arterial tree
۴. MRI for the assessment of aortic stiffness and pulsatile hemodynamics
۵. Computed tomography of the aorta
۶. Radionuclide-based imaging of the aortic wall
۷. Arterial wall stiffness: basic principles and methods of measurement in vivo
۸. Ambulatory measurement of pulsatile hemodynamics
۹. Animal models and methods to study arterial stiffness
۱۰. Hemodynamic role of the aorta
۱۱. Wave reflection in the arterial tree
۱۲. Linking arterial stiffness to microvascular remodeling
۱۳. Myocardial function: from myofilaments to cardiac pump
۱۴. Systolic-diastolic coupling
۱۵. Ventricular-arterial coupling: the pressure-volume plane
۱۶. Myocardial wall stress and the systolic loading sequence
۱۷. Assessment of ventricular arterial interactions via arterial pressure-flow relations in humans
۱۸. Hemodynamic determinants of myocardial oxygen demand and supply
۱۹. Role of elastin and elastin-derived peptides in arterial stiffness: from synthesis to potential therapeutic in
۲۰. Inflammation and arterial stiffness
۲۱. Mechanisms of calcification in the aortic wall and aortic valve
۲۲. Vascular smooth muscle cell dysfunction: role in arterial stiffening and cardiovascular disease
۲۳. Endothelial cell dysfunction and senescence: biologic mechanisms and hemodynamic consequences
۲۴. Autonomic and neuroendocrine modulation of arterial stiffness and hemodynamics
۲۵. Cellular mechanisms of aging and their impact on the aortic/arterial wall
۲۶. Normal aging: arterial stiffness and remodeling over the life course
۲۷. Early vascular aging and supernormal vascular aging: genetics, epigenetics, and the environment
۲۸. Ethnic differences in arterial stiffness and central aortic hemodynamics
۲۹. Arterial stiffness and pulsatile hemodynamics in systemic hypertension
۳۰. Arterial stiffness and pulsatile hemodynamics in diabetes and obesity
۳۱. Cardiovascular risk prevention in clinical medicine: current guidelines in the United States and in Europe
۳۲. Cardiovascular risk prevention in clinical medicine: current guidelines in Asia
۳۳. Arterial stiffness for cardiovascular risk stratification in clinical practice
۳۴. Role of the heart and arterial tree in physiologic adjustments during exercise
۳۵. Invasive hemodynamic assessments during exercise: normal patterns and clinical value
۳۶. Arterial stiffness and pulsatile hemodynamics in heart failure
۳۷. Ventricular-arterial coupling and arterial load in aortic valve disease
۳۸. Arterial stiffness and atherosclerosis: mechanistic and pathophysiologic interactions
۳۹. Arterial stiffness and pulsatile hemodynamics in coronary artery disease and other forms of atherosclerotic va
۴۰. Arterial stiffness and pulsatile hemodynamics in renal disease
۴۱. Arterial stiffness, pulsatile hemodynamics, and the vascular contributions to dementia
۴۲. Arterial stiffness and pulsatile hemodynamics in pregnancy and pregnancy-related vascular complications
۴۳. Arterial stiffness and pulsatile hemodynamics in pediatric populations
۴۴. Aortopathies and arteriopathies
۴۵. Arterial stiffness and pulsatile hemodynamics in thoracic aortopathies
۴۶. Arterial stiffness and pulsatile hemodynamics in congenital heart disease
۴۷. Infection and arterial stiffness
۴۸. Arterial stiffness, hemodynamics, and microvascular complications in conditions characterized by low arterial
۴۹. Effects of common antihypertensive treatments on pulsatile arterial hemodynamics
۵۰. Pharmacologic approaches to reduce arterial stiffness
۵۱. Organic and dietary nitrates, inorganic nitrite, nitric oxide donors, and soluble guanylate cyclase stimulation
۵۲. Effect of exercise training and weight loss on arterial stiffness and pulsatile hemodynamics
۵۳. Dietary salt and arterial stiffness
۵۴. Role of arterial stiffness and central hemodynamics in personalized medicine in hypertension
۵۵. Pulsatile hemodynamics and ventricular-arterial interactions in the pulmonary circulation: physiologic concepts
۵۶. Pulmonary arterial load and ventricular-arterial coupling in pulmonary hypertension
۵۷. Biologic mechanisms and consequences of pulmonary artery stiffening in pulmonary hypertension
۵۸. Therapeutic approaches to improve pulmonary arterial load and right ventricular-pulmonary arterial coupling