Make sure you are thoroughly prepared to work in a clinical laboratory. Rodak’s Hematology: Clinical Principles and Applications, 7th Edition uses hundreds of full-color photomicrographs to help you understand the essentials of hematology and hemostasis. This new edition details the parts and functions of the cell; shows how to accurately identify cells; covers normal hematopoiesis through diseases of erythroid, myeloid, lymphoid, and megakaryocytic origins; and simplifies hemostasis and thrombosis concepts and disorders. Easy to follow and understand, this book also covers key topics, including working in the hematology and hemostasis laboratory; complementary testing areas such as flow cytometry, cytogenetics, and molecular diagnostics; and laboratory testing of blood cells and body fluid cells.

• Content throughout the text reflects the latest information on hematology and hemostasis.
• Hematology and hemostasis instruments are described, compared, and contrasted.
• More than 700 full-color illustrations and photomicrographs make it easier to visualize hematology concepts and show what you’ll encounter in the laboratory.
• Instructions for laboratory procedures include detailed figures and sources of errors.
• Case studies in each chapter provide opportunities to apply hematology concepts to real-life scenarios.
• Hematology and hemostasis reference intervals are listed on the inside front and back covers for quick reference.
• Bulleted chapter summaries make it easy for you to review important points.
• Learning objectives begin each chapter and indicate what you should achieve, with review questions appearing at the end.
• Appendices provide easy access to a list of key formulas, abbreviations, and a detailed glossary to complement learning.

New to this edition

• NEW! Chapter on Patient Safety in Hematology and Hemostasis.
• NEW! Section on hematology and hemostasis in transgender populations.
• UPDATED! White blood cell chapters are current with the 2022 World Health Organization (WHO) Classification of Haematolymphoid Tumours.
• NEW! Changes in laboratory results associated with COVID-19 and other viral infections.
• NEW! Content and figures on plasma transport, cell communication, and signal transduction.
• NEW! Coverage of CRISPR technology for treatment of hemoglobinopathies and thalassemia.
• UPDATED! Major revision of the Automated Blood Cell Analysis chapter.

Contents

۱. An overview of clinical laboratory hematology
۲. Quality assurance in hematology and hemostasis testing
۳. Cellular structure and function
۴. Hematopoiesis
۵. Erythrocyte production and destruction
۶. Erythrocyte metabolism and membrane structure and function
۷. Hemoglobin metabolism
۸. Iron kinetics and laboratory assessment
۹. Leukocyte development, kinetics, and functions
۱۰. Platelet production, structure, and function
۱۱. Manual, semiautomated, and point-of-care testing in hematology
۱۲. Automated blood cell analysis
۱۳. Examination of the peripheral blood film and correlation with the complete blood count
۱۴. Bone marrow examination
۱۵. Body fluid analysis in the hematology laboratory
۱۶. Anemias: Red blood cell morphology and approach to diagnosis
۱۷. Disorders of iron kinetics and heme metabolism
۱۸. Anemias caused by defects of DNA metabolism
۱۹. Bone marrow failure
۲۰. Introduction to increased destruction of erythrocytes
۲۱. Intrinsic defects leading to increased erythrocyte destruction
۲۲. Extrinsic defects leading to increased erythrocyte destruction—nonimmune causes
۲۳. Extrinsic defects leading to increased erythrocyte destruction—immune causes
۲۴. Hemoglobinopathies (structural defects in hemoglobin)
۲۵. Thalassemias
۲۶. Nonmalignant leukocyte disorders
۲۷. Introduction to hematologic neoplasms
۲۸. Flow cytometric analysis in hematologic disorders
۲۹. Molecular diagnostics in hematopathology
۳۰. Cytogenetics/cytogenomics
۳۱. Acute leukemias
۳۲. Myeloproliferative neoplasms
۳۳. Myelodysplastic syndromes
۳۴. Mature lymphoid neoplasms
۳۵. Normal hemostasis
۳۶. Hemorrhagic disorders and laboratory assessment
۳۷. Qualitative disorders of platelets and vasculature
۳۸. Thrombocytopenia and thrombocytosis
۳۹. Thrombotic disorders and laboratory assessment
۴۰. Antithrombotic therapies and their laboratory assessment
۴۱. Laboratory evaluation of hemostasis
۴۲. Hemostasis and coagulation instrumentation
۴۳. Hematology and hemostasis in the pediatric, geriatric, and pregnant populations

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