Kidney disease and cancer are frequent comorbidities that require specialized knowledge and expertise from both the nephrologist and the oncologist. Written by three pioneers in this growing subspecialty, Onco-Nephrology provides authoritative, definitive coverage of the mechanism and management of these two life-threatening diseases. This unique, single-volume resource covers current protocols and recommends management therapies to arrest kidney failure and allow oncologic treatments to continue and succeed.

• Addresses acute and chronic kidney diseases that develop from a variety of cancers. This includes direct kidney injury from the malignancy, paraneoplastic effects of the cancer, and various cancer agents used to treat the malignancy.
• Discusses key issues regarding kidney disease in patients with cancer, including conventional chemotherapeutic regimens and new novel therapies (targeted agents and immunotherapies) or the malignancies themselves that may promote kidney injury; patients with chronic kidney disease who acquire cancer unrelated to renal failure; and kidney transplantation, which has been shown to carry an increased risk of cancer.
• Contains dedicated chapters for each class of the conventional chemotherapeutic agents, targeted cancer agents, and cancer immunotherapies including the basic science, pathogenic mechanisms of injury, clinical manifestations, and treatment.
• Includes special chapters devoted to the individual classes of chemotherapies that relate to kidney disease for quick reference. Discusses increasingly complex problems due to more numerous and specialized anti-cancer drugs, as well as increased survival rates for both cancer and renal failure requiring long-term patient care.
• Covers anti-VEGF (antivascular endothelial growth factor) agents and cancer immunotherapies – treatments that are being recognized for adverse kidney effects.
• Utilizes a clear, logical format based on the ASN Core Curriculum for Onco-Nephrology, making this reference an excellent tool for board review, as well as a practical resource in daily practice.

Contents

۱. Kidney function
۲. Dysnatremias in cancer
۳. Potassium disorders
۴. Calcium and phosphorus disorders
۵. Volume disorders and fluid resuscitation
۶. Paraproteins
۷. Cast nephropathy
۸. Systemic light chain amyloidosis
۹. Monoclonal immunoglobulin deposition disease
۱۰. Fibrillary and immunotactoid glomerulonephritis
۱۱. Hematopoietic cell transplant associated kidney injury
۱۲. Sinusoidal obstruction syndrome
۱۳. Thrombotic microangiopathy
۱۴. Graft-versus-host disease
۱۵. Chronic kidney disease, end-stage renal disease, and bone marrow transplant
۱۶. Conventional chemotherapy
۱۷. Targeted cancer therapies (biologics)
۱۸. Adverse kidney effects of immunotherapies
۱۹. Chemotherapy in chronic kidney disease and dialysis
۲۰. Radiation nephropathy
۲۱. Paraneoplastic glomerular diseases
۲۲. Paraneoplastic glomerulonephritis
۲۳. Hematologic malignancies
۲۴. Cancer screening recommendations
۲۵. Renal cell cancer
۲۶. Wilms tumor and von Hippel Lindau disease
۲۷. Tuberous sclerosis complex and the kidney
۲۸. Evaluation of a renal cyst/mass
۲۹. Acute kidney injury incidence, pathogenesis, and outcomes
۳۰. Tumor lysis syndrome
۳۱. Obstructive nephropathy in cancer
۳۲. Renal replacement therapies
۳۳. Chronic kidney disease as a complication of cancer, with special focus on kidney and urothelial tumors
۳۴. Incidence of cancer and screening recommendations
۳۵. Cancer in renal transplant patients
۳۶. Renal infections in cancer patients
۳۷. Kidney disease in leukemia
۳۸. Kidney disease in lymphoma