This is an updated and abridged edition of the original volume published in 2004. Like its predecessor it is targeted for students of bioengineering, biomedical engineering, applied physiology, biological cybernetics and related fields; for engineers and scientists who have an interest in neuroprosthetics; and for medical practitioners using products of that field.

The practice of neuroprosthetics requires a fundamental understanding of the anatomy and physiology of the nervous system, mathematical neurobiology, material science, electrochemistry, and electrophysiology. The text assumes some familiarity with basic anatomy, physiology, calculus, electrophysiology and bioinstrumentation, which typically are covered in undergraduate and first year graduate bioengineering curricula. These areas are also reviewed here, with the aim of consolidating principles fundamental to understanding the field. With that as background, the book then presents an overview of the field with detailed emphasis in selected areas of neural interfaces and neuroprostheses. The covered topics provide readers with sufficient information to understand the theory, rationale, design, and functioning of neuroprosthetic devices currently in clinical use and under development.

The current volume is shorter than its predecessor. This has been achieved by reducing some of the repetition present in certain chapters of the earlier edition and eliminating a few chapters whose topics are now well covered in review literature readily available on the internet and elsewhere. Two chapters have been retained in their original versions to provide important background material, but the remaining chapters have either been revised by their original authors or replaced by new versions written by different authors. In addition new topics have been added to the section on existing systems.

Contents

۱. Peripheral Nervous System (Ken Horch)
۲. The Autonomic Nervous System (Kip Ludwig, Erika Ross, Nicholas Langhals, Doug Weber, J Luis Lujan and Dmitrios Georgakopoulos)
۳. Anatomy and Physiology of the Central Nervous System (Doug Weber, James Harris, Tim Bruns and Vivian Mushahwar)
۴. Muscle (Bethany R Kondiles, Amirali Toossi, Vivian K Mushahwar and Stanley Salmons)
۵. Somatic Sensation (Sliman J Bensmaia and Kenneth W Horch)
۶. Visual System (Boshuo Wang and James D Weiland)
۷. The Auditory System (Bryony A Nayagam, Andrew K Wise and Robert K Shepherd)
۸. Neuroplasticity (Pablo A Celnik, Michael J Makey, Esteban Fridman and Leonardo G Cohen)
۹. Passive Models of Excitable Cells (Johannes Jan Struijk)
۱۰. Conductive and Insulative Materials (Stuart F Cogan)
۱۱. The Biocompatibility of Intracortical Microelectrode Recording Arrays for Brain Machine Interfacing (John L Skousen and Patrick A Tresco)
۱۲. Peripheral Nerve Stimulation (Dustin J Tyler)
۱۳. Central Nervous System Stimulation (Andrew S Koivuniemi and Kevin J Otto)
۱۴. Peripheral Nerve Recording Electrodes and Techniques (Ken Yoshida, Michael J Bertram, T G Hunter Cox and Ronald R Riso)
۱۵. CNS Recording: Devices and Techniques (Daryl R Kipke)
۱۶. Skeletal Motor Neuroprostheses (Kevin L Kilgore, Robert F Kirsch and P Hunter Peckham)
۱۷. Neuroprosthetic Control of Lower Urinary Tract Function (James A Hokanson, Cindy L Amundsen and Warren M Grill)
۱۸. Neuroprosthetic Control of Respiratory Muscles (Anthony F DiMarco and Graham H Creasey)
۱۹. Vagus Nerve Stimulation: Therapeutic Applications for Cardiac Disease (Ray W Chui, Pradeep S Rajendran, Una Buckley, Kalyanam Shivkumar and Jeffrey L Ardell )
۲۰. Visual Prostheses (Boshuo Wang and James D Weiland)
۲۱. Restoring Hearing with Neural Prostheses: Current Status and Future Directions (Hubert H Lim, Meredith E Adams, Peggy B Nelson and Andrew J Oxenham)
۲۲. Spinal Cord Stimulation for Pain Control (John L Parker)
۲۳. Deep Brain Stimulation (Julia P Slopsema and Matthew D Johnson)
۲۴. Prosthetic Limbs (Sanford G Meek)
۲۵. Stimulation of the Spinal Cord for the Control of Walking (Ashley N Dalrymple and Vivian K Mushahwar)
۲۶. Brain Computer Interfaces (Dan Moran)
۲۷. Gastric and Cardio-Vascular Muscle Stimulation (Amirali Toossi, Bethany R Kondiles and Vivian K Mushahwar)
۲۸. Medical Device Regulations and Biocompatibility Testing Requirements Focus on Neuroprotheses (Jeffery R Nelson and Jerry R Nelson)