Motor Neuron Disease in Adults reviews new information as it applies to all aspects of motor neuron disease (ALS, PLS, PMA). The choice of articles is for those that use evidence-based methods to ensure that the new information is solid and advances the topic or issue. The book can be used by anyone who provides any type of care to ALS patients. In particular, neurologists will find the latest information on diagnosis and management, as well as new information on genetics and frontotemporal lobe involvement. Allied health providers will find useful information for their discipline. Patients will also find both specific and general information to help understand what they are experiencing and how to help manage their symptoms.

Review

About the Author

Contents

۱ History of the Recognition of Motor Neuron Disease
۲ Nomenclature and Classification of Motor Neuron Disease
۳ Clinical Anatomy, Physiology, and Pathology of Motor Neuron Disease
۴ Clinical Features of Motor Neuron Disease
۵ Frontotemporal Dysfunction and Dementia in Amyotrophic Lateral Sclerosis
۶ Laboratory Tests for Motor Neuron Disease
۷ Biomarkers for Motor Neuron Disease
& Imaging in Motor Neuron Disease
۹ Diagnostic Criteria for Motor Neuron Disease
۱۰ Differential Diagnosis of Motor Neuron Disease
۱۱ Motor Neuron Disease Progression
۱۲ Epidemiology of Amyotrophic Lateral Sclerosis
۱۳ Genetics of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
۱۴ Genome-wide Approaches to Identify Amyotrophic Lateral Sclerosis-associated Genes
۱۵ Pathology of Amyotrophic Lateral Sclerosis and Frontotemporal Lobar Degeneration
۱۶ Convergence and Divergence in Amyotrophic Lateral Sclerosis Syndrome: Genetics, Molecular Pathways, and Molecular Mechanisms
۱۷ Immunologic Aspects of Amyotrophic Lateral Sclerosis
۱۸ Cyanobacteria, Amyotrophic Lateral Sclerosis, and the BMAA Hypothesis
۱۹ Animal Models of Adult Motor Neuron Disease
۲۰ Multidisciplinary Clinics and Practice Parameters and Guidelines
۲۱ Allied Health and Other Providers
۲۲ Respiratory Assessment and Management
۲۳ Nutritional Assessment and Management
۲۴ Communication Assessment and Management
۲۵ Psychological and Psychiatric Assessment and Management
۲۶ Symptoms and Management
۲۷ Intimacy, Sexuality, and Pregnancy
۲۸ Quality of Life
۲۹ Caregiver Issues
۳۰ End-of-Life Care
۳۱ Costs of Amyotrophic Lateral Sclerosis Care
۳۲ Clinical Trial Designs in Amyotrophic Lateral Sclerosis
۳۳ Stem Cell Therapy for Motor Neuron Disease