Edited by physiology instructors who are also active clinicians, Integrated Physiology and Pathophysiology is a one-stop guide to key information you need for early clinical and medical training and practice. This unique, integrated textbook unites these two essential disciplines and focuses on the most relevant aspects for clinical application. A concise, review-like format, tables and diagrams, spaced repetition for effective learning, and self-assessment features help you gain and retain a firm understanding of basic physiology and pathophysiology. Integrated Physiology and Pathophysiology works equally well as a great starting point in your studies and as a review for boards.

• Shares the knowledge and expertise of an outstanding editorial team consisting of two practicing clinicians who also teach physiology and pathophysiology at Harvard Medical School, plus a top Harvard medical student.
• Provides an integrated approach to physiology and pathophysiology in a concise, bulleted format. Chapters are short and focus on clinically relevant, foundational concepts in clear, simple language.
• Employs focused repetition of key points, helping you quickly recall core concepts such as pressure-flow-resistance relationships, ion gradients and action potentials, and mass balance. You’ll revisit these concepts in a variety of meaningful clinical contexts in different chapters; this “spaced learning” method of reinforcement promotes deeper and more flexible understanding and application.
• Includes Fast Facts boxes that emphasize take-home messages or definitions.
• Contains Integration boxes that link physiology and pathophysiology to pharmacology, genetics, and other related sciences.
• Presents clinical cases and with signs and symptoms, history, and laboratory data that bring pathophysiology to life.
• Features end-of-chapter board-type questions, complete with clear explanations of the answers, to help prepare you for standardized exams.

Contents

۱. General principles of physiology
۱. ۱. Introduction to diagnosis
۲. An overview of nerve cell physiology and electrophysiology
۳. Central nervous system
۴. Peripheral nervous system and autonomic nervous system
۵. The neuromuscular junction and skeletal muscle
۶. Smooth muscle
۶. ۱. Musculoskeletal physiology
۷. Blood and hemostasis
۸. The lymphatic system and the immune system
۸. ۱. Blood and lymph
۹. The vasculature
۱۰. The heart as a pump
۱۱. Cardiac electrophysiology
۱۲. Exercise physiology
۱۲. ۱. Cardiac physiology
۱۳. The mechanics of breathing
۱۴. Gas exchange in the lung
۱۵. Gas transport
۱۶. The regulation of breathing
۱۶. ۱. Pulmonary physiology
۱۷. Renal structure and function
۱۸. Tubular transport
۱۹. The regulation of blood pressure and extracellular fluid volume
۲۰. Osmoregulation
۲۱. The regulation of potassium balance
۲۲. Acid-base homeostasis
۲۳. Micturition
۲۳. ۱. Renal physiology
۲۴. Nutrition, digestion, and absorption
۲۵. Control of gastrointestinal motility and secretion
۲۶. Hepatic physiology
۲۷. The gastrointestinal immune system
۲۷. ۱. Gastrointestinal physiology
۲۸. The endocrine pancreas: Fed and fasted metabolic states
۲۹. The pituitary gland
۳۰. The thyroid gland
۳۱. The adrenal gland
۳۲. Calcium regulation: Parathyroid physiology
۳۳. Calcium regulation: Bone physiology
۳۴. The female reproductive system
۳۵. Pregnancy and parturition
۳۶. The male reproductive system
۳۶. ۱. Endocrine physiology