In recent years there has been recognition of the central role of imaging in the management of patients with cancer. The third edition of this widely acclaimed book builds on the foundations laid down by the first edition, the 1998 winner of the Royal Society’s award for the Multi-author Textbook of the Year, and the second (2004). The core of the book deals with the application of imaging in all tumours. An extensively referenced, evidence-based analysis is given of the role of imaging in planning treatment. Experienced opinion is provided as to the advantages and limitations of all relevant imaging modalities including ultrasound, CT, MRI, PET/CT and other nuclear medicine techniques.

Imaging in the recognition of metastatic disease is covered in detail with chapters detailing the range of appearances of deposits in each organ. Much attention is given to the differential diagnosis of focal pathology in each organ in patients with underlying malignancy and useful protocols for the performance of the study provided.

While including a section on new horizons in cancer imaging, such as the imaging of angiogenesis, MR lymphography and the rapidly evolving field of molecular imaging, the editors have not neglected the more traditional general principles of cancer behaviour and imaging. Hence, an outline of cancer surgery, chemotherapy and radiotherapy is provided by experts. As therapy becomes more successful, increasingly important issues for the radiologist such as the assessment of response, the effect of treatment on normal tissues, the complications of treatment, and the risk of second malignancies are presented.

There are several outstanding features to this book: the colour diagrams of the staging systems are exquisite and allow the often complex systems to be understood easily and memorized; the organization of the book into different, clearly defined sections allow it to be used not only as a reliable reference text, but also to be read easily; key points and summaries in point form are provided throughout for quick revision.

This comprehensive book will not only be essential reading for all radiologists, but also important for all members of a multidisciplinary team looking after patients with cancer.

Features

• Includes a brand new section on Functional Imaging
• Arranged into 9 clearly defined sections: general principles, primary tumour evaluation and staging, haematology malignancy, paediatrics, metastases, imaging and treatment, effects of treatment on normal tissue, the immuno-compromised host, and functional imaging
• Extensively referenced and evidence based
• Includes over 2500 images
• Professor Dame Janet Husband has led pioneering clinical research both in CT and MRI in cancer care and is subsequently one of the world’s leading oncologic imagists

Winner of the Royal Society of Medicine Award for multi-author textbook of the year

Contents

Preface  Foreword from the 2nd edition  Foreword for the 3rd edition  PART I – GENERAL PRINCIPLES  ۱. Trends in cancer incidence, survival and mortality  ۲. Staging of Cancer  ۳. Multidisciplinary treatment of cancer: Surgical  ۴. Multidisciplinary treatment of cancer: Chemptherapy  ۵. Multidisciplinary treatment of cancer: Radiotherapy  ۶. Assesment of Response to Treatment  ۷. Second maliginacies  PART II – PRIMARY TUMOUR EVALUATION AND STAGING  ۸. Lung cancer  ۹. Mediastinal Tumours  ۱۰. Pleaural tumours  ۱۱. Oesphogeal Cancer  ۱۲. Gastric Cancer  ۱۳. Colorectal Cancer  ۱۴. Primary Tumours of the Liver and Biliary Tract  ۱۵. Renal Tumours  ۱۶. Primary Adrenal Malignancy  ۱۷. Pancreatic Malignancy  ۱۸. Bladder Cancer  ۱۹. Prostate Cancer  ۲۰. Testicular germ cell tumours  ۲۱. Ovarian Cancer  ۲۲. Uterine and Cervical Tumours  ۲۳. Primary Retroperitoneal Tumours  ۲۴. Primary Bone Tumours  ۲۵. Soft Tissue Sarcomas  ۲۶. Breast Cancer  ۲۷. Paranasal Sinus Neoplasms  ۲۸. Tumours of the Pharynx, Tongue and Mouth  ۲۹. Laryngeal Tumours  ۳۰. Thyroid Cancer  ۳۱. Primary Tumours of the Central Nervous System  ۳۲. Neuroendocrine Tumours  PART III – HAEMATOLOGY MALIGNANCY  ۳۳. Lymphoma  ۳۴. Multiple Myeloma  ۳۵. Leukaemia  PART IV – PAEDIATRICS  ۳۶. General Principles in Paediatric Oncology  ۳۷. Wilm’s Tumour and Associated Neoplasms of the Kidney  ۳۸. Neuroblastoma  ۳۹. Uncommon Paediatric Neoplasms  PART V – METASTASES  ۴۰. Lymph node Metastases  ۴۱. Lung and Pleural Metastases  ۴۲. Bone Metastases  ۴۳. Liver Metastases  ۴۴. Metastatic effects on the Nervous System  ۴۵. Adrenal Metastases  ۴۶. Peritoneal Metastases  ۴۷. Spleen  ۴۸. Malignant Tumours of the Skin  ۴۹. Radiological Investigation of Carcinoma of Unknown Primary Site  PART VI – IMAGING AND TREATMENT  ۵۰. Interventional Imaging: General Applilcations  ۵۱. Interventional Imaging: Tumour Ablation  ۵۲. Imaging for Radiotherapy Treatment Planning  ۵۳. Radiological Manifestations of Acute Complications of Treatment  PART VII – EFFECTS OF TREATMENT ON NORMAL TISSUE  ۵۴. Effects of Treatment on Normal Tissue:  Thorax  ۵۵. Bone and Bone Marrow  ۵۶. Abdomen and Pelvis  PART VIII – THE IMMUNOCOMPROMISED HOST  ۵۷. The Immunocompromised Host: Clinical Considerations  ۵۸. The Immunocompromised: Central Nervous System  ۵۹. The Immunocompromised Host: Chest  ۶۰. The Immunocompromised Host: Abdomen and Pelvis  PART IX – FUNCTIONAL IMAGING  ۶۱. Positron Emission Tomography – Principles and Clinical Applications  ۶۲. Functional Imaging: Clincal Applications in Molecular Targeted Therapy  ۶۳. Measurement of Angiogensis- MRI Principles & Practice  ۶۴. Measurement of angiogenesis – CT principles and practice  ۶۵. Magnetic resonance: Emerging technologies and applications