The largest collection of basic, clinical, and applied knowledge on the chemical senses ever compiled in one volume, the third edition of Handbook of Olfaction and Gustation encompass recent developments in all fields of chemosensory science, particularly the most recent advances in neurobiology, neuroscience, molecular biology, and modern functional imaging techniques. Divided into five main sections, the text covers the senses of smell and taste as well as sensory integration, industrial applications, and other chemosensory systems. This is essential reading for clinicians and academic researchers interested in basic and applied chemosensory perception.

Contents

Part 1 General Introduction

۱ Introduction and Historical Perspective 3

Part 2 Olfactory Anatomy and Neurobiology

۲ Anatomy of the Nasal Passages in Mammals 39
۳ Olfactory Mucosa: Composition, Enzymatic Localization, and Metabolism 63
۴ Development, Morphology, and Functional Anatomy of the Olfactory Epithelium 93
۵ Olfactory Receptor Function 109
۶ Odorant Receptor Gene Regulation 123
۷ Neurogenesis in the Adult Olfactory Epithelium 133
۸ Anatomy and Neurobiology of the Main and Accessory Olfactory Bulbs 157
۹ Adult Neurogenesis in the Subventricular Zone and Migration to the Olfactory Bulb 183
۱۰ Cortical Olfactory Anatomy and Physiology 209

Part 3 Human Olfactory Measurement, Physiology, and Development

۱۱ Psychophysical Measurement of Human Olfactory Function 227
۱۲ Electrophysiological Measurement of Olfactory Function 261
۱۳ Structural and Functional Imaging of the Human Olfactory System 279
۱۴ Prenatal and Postnatal Human Olfactory Development: Influences on Cognition and Behavior 305
۱۵ Olfactory Memory 337

Part 4 Clinical Applications and Perspectives

۱۶ Nasal Patency and the Aerodynamics of Nasal Airflow in Relation to Olfactory Function 355
۱۷ Clinical Disorders of Olfaction 375
۱۸ Odor Perception and Neuropathology in Neurodegenerative Diseases and Schizophrenia 403
۱۹ The Olfactory System as a Route of Delivery for Agents to the Brain and Circulation 453
۲۰ Influence of Toxins on Olfactory Function and their Potential Association with Neurodegenerative Disease 485

Part 5 Olfaction in Nonhuman Forms

۲۱ Microbial Chemical Sensing 513
۲۲ Olfaction in Insects 531
۲۳ Olfaction in Aquatic Vertebrates 547
۲۴ The Chemistry of Avian Odors: An Introduction to Best Practices 565
۲۵ Olfactory Communication in Rodents in Natural and Semi-Natural Habitats 579
۲۶ Olfaction in the Order Carnivora: Family Canidae 591
۲۷ Olfaction in Nonhuman Primates 605

Part 6 Gustation

۲۸ The Role of Saliva in Taste Transduction 625
۲۹ Anatomy of the Tongue and Taste Buds 637
۳۰ Chemical Modulators of Taste 665
۳۱ The Molecular Basis of Gustatory Transduction 685
۳۲ Central Taste Anatomy and Physiology of Rodents and Primates 701
۳۳ Development of the Taste System 727

Part 7 Human Taste Measurement, Physiology, and Development

۳۴ Psychophysical Measures of Human Oral Sensation 751
۳۵ Mapping Brain Activity in Response to Taste Stimulation 775
۳۶ The Ontogeny of Taste Perception and Preference Throughout Childhood 795

Part 8 Clinical Applications and Perspectives

۳۷ Nutritional Implications of Taste and Smell Dysfunction 831
۳۸ Conditioned Taste Aversions 865
۳۹ Clinical Disorders Affecting Taste: An Update 887
۴۰ Influence of Drugs on Taste Function 911

Part 9 Taste in Nonhuman Species

۴۱ Taste Processing in Insects 929
۴۲ Taste in Aquatic Vertebrates 947
۴۳ Comparative Taste Biology with Special Focus on Birds and Reptiles 957
۴۴ Functional Organization of the Gustatory System in Macaques 983

Part 10 Central Integration of Olfaction, Taste, and the Other Senses

۴۵ Chemosensory Integration and the Perception of Flavor 1007
۴۶ Neural Integration of Taste, Smell, Oral Texture, and Visual Modalities 1027

Part 11 Industrial Applications and Perspectives

۴۷ Olfaction and Taste in the Food and Beverage Industries 1051
۴۸ Olfaction and Gustation in the Flavor and Fragrance Industries 1067
۴۹ The Smell and Taste of Public Drinking Water 1079

Part 12 Other Chemosensory Systems

۵۰ Trigeminal Chemesthesis 1091
۵۱ The Vomeronasal Organ 1113
۵۲ The Septal Organ, Grueneberg Ganglion, and Terminal Nerve 1133