Improvements in the detection of fetal and neonatal brain injuries, advances in our understanding of the pathophysiology, cellular and molecular bases of encephalopathy, and new treatment options have all combined to produce significant changes in the management of neonatal brain disorders in the past few years. This new edition of Fetal and Neonatal Brain Injury brings the reader fully up to date with all advances in clinical management and outcome assessment. Updated material includes inflammation focusing in particular on chorioamnionitis and fetal brain injury; genetic brain injury; and expanded sections on cholestasis, diabetes, and thyroid disease. An updated, highly illustrated chapter on structural and functional imaging of the fetal and neonatal brain is also included. An outstanding international team of highly experienced neonatologists and maternal-fetal medicine clinicians have produced a practical, authoritative clinical text that gives clear management advice to all clinicians involved in the treatment of these patients.

Book Description

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Contents

Chapter 1 Neonatal Encephalopathy
Chapter 2 Neuronal Cell Death Mechanisms Relevant to Humans
Chapter 3 Cellular and Molecular Biology of Hypoxic-Ischemic Encephalopathy
Chapter 4 The Pathogenesis of Preterm Brain Injury
Chapter 5 Prematurity and Complications of Labor and Delivery
Chapter 6 Risks and Complications of Multiple Gestation
Chapter 7 Intrauterine Growth Restriction
Chapter 8 Maternal Diseases that Affect Fetal and Neonatal Neurodevelopment
Chapter 9 Obstetric Conditions and Practices that Affect the Fetus and Newborn
Chapter 10 Fetal and Neonatal Injury as a Consequence of Maternal Substance Abuse
Chapter 11 Hypertensive Disorders of Pregnancy
Chapter 12 Complications of Labor and Delivery
Chapter 13 Fetal Responses to Asphyxia
Chapter 14 Antepartum Evaluation of Fetal Well-Being
Chapter 15 Intrapartum Evaluation of the Fetus
Chapter 16 Clinical Manifestations of Hypoxic-Ischemic Encephalopathy
Chapter 17 The Use of EEG and aEEG in Assessing the Term and Preterm Brain
Chapter 18 Neuroimaging in the Evaluation of Pattern and Timing of Fetal and Neonatal Brain Abnormalities
Chapter 19 Light-Based Assessment of the Brain
Chapter 20 Placental Pathology and the Etiology of Fetal and Neonatal Brain Injury
Chapter 21 Timing Perinatal Hypoxic-Ischemic Brain Injury
Chapter 22 Congenital Malformations of the Brain
Chapter 23 Neurogenetic Disorders of the Brain
Chapter 24 Hemorrhagic Lesions of the Central Nervous System
Chapter 25 Neonatal Stroke
Chapter 26 Neurodevelopmental Consequences of Neonatal Hypoglycemia
Chapter 27 Hyperbilirubinemia and Kernicterus
Chapter 28 Polycythemia and Fetal-Maternal Bleeding
Chapter 29 Hydrops Fetalis
Chapter 30 Bacterial Sepsis in the Neonate
Chapter 31 Neonatal Bacterial Meningitis
Chapter 32 Neurologic Sequelae of Congenital and Perinatal Infections
Chapter 33 Neurologic Complications of Perinatal Human Immunodeficiency Virus Infection
Chapter 34 Inborn Errors of Metabolism and Single-Gene Disorders with Features of Neonatal Encephalopathy
Chapter 35 Acidosis and Alkalosis
Chapter 36 Persistent Pulmonary Hypertension of the Newborn
Chapter 37 Pediatric Cardiac Surgery
Chapter 38 Neonatal Resuscitation
Chapter 39 Improving Performance, Reducing Error, and Minimizing Risk in the Delivery Room
Chapter 40 Extended Management Following Resuscitation
Chapter 41 Endogenous and Exogenous Neuroprotective Mechanisms after Hypoxic-Ischemic Injury
Chapter 42 Neonatal Seizures
Chapter 43 Nutritional Support of the Asphyxiated Infant
Chapter 44 Early Outcomes after Extremely Preterm Birth
Chapter 45 Cerebral Palsy
Chapter 46 Neurodevelopmental and Neurobehavioral Outcomes of Prematurity
Chapter 47 Neurocognitive Outcomes in Term Infants with Neonatal Encephalopathy
Chapter 48 Neonatal Neuroethics
Chapter 49 Medicolegal Issues in Perinatal Brain Injury