Diffusion MRI remains the most comprehensive reference for understanding this rapidly evolving and powerful technology and is an essential handbook for designing, analyzing, and interpreting diffusion MR experiments.

Diffusion imaging provides a unique window on human brain anatomy. This non-invasive technique continues to grow in popularity as a way to study brain pathways that could never before be investigated in vivo.

This book covers the fundamental theory of diffusion imaging, discusses its most promising applications to basic and clinical neuroscience, and introduces cutting-edge methodological developments that will shape the field in coming years. Written by leading experts in the field, it places the exciting new results emerging from diffusion imaging in the context of classical anatomical techniques to show where diffusion studies might offer unique insights and where potential limitations lie.

• Fully revised and updated edition of the first comprehensive reference on a powerful technique in brain imaging
• Covers all aspects of a diffusion MRI study from acquisition through analysis to interpretation, and from fundamental theory to cutting-edge developments
• New chapters covering connectomics, advanced diffusion acquisition, artifact removal, and applications to the neonatal brain
• Provides practical advice on running an experiment
• Includes discussion of applications in psychiatry, neurology, neurosurgery, and basic neuroscience
• Full color throughout

Review

“This text outlines the theory and applications of diffusion magnetic resonance imaging (MRI). In 25 chapters, radiologists, neuroscientists, psychologists, psychiatrists, and others from North America, Europe, and Israel outline the methods underlying diffusion imaging; the use of diffusion MRI for quantitative measurement and in understanding neurological disorders…”–ProtoView.com, April 2014

From the Back Cover

Diffusion MRI remains the most comprehensive reference for understanding this rapidly evolving and powerful technology and is an essential handbook for designing, analyzing, and interpreting diffusion MR experiments.

Diffusion imaging provides a unique window on human brain anatomy. This non-invasive technique continues to grow in popularity as a way to study brain pathways that could never before be investigated in vivo.

This book covers the fundamental theory of diffusion imaging, discusses its most promising applications to basic and clinical neuroscience, and introduces cutting-edge methodological developments that will shape the field in coming years. Written by leading experts in the field, it places the exciting new results emerging from diffusion imaging in the context of classical anatomical techniques to show where diffusion studies might offer unique insights and where potential limitations lie.

Contents

۱. Introduction to diffusion MR
۲. Pulse Sequences for Diffusion-Weighted MRI
۳. Diffusion Acquisition: Pushing the Boundaries
۴. Geometric Distortions in Diffusion MRI
۵. Gaussian Modeling of the Diffusion Signal
۶. Multiple Fibers: Beyond the Diffusion Tensor

Section II: Diffusion MRI for Quantitative Measurement

۷. White Matter Structure: A Microscopist’s View
۸. The Biological Basis of Diffusion Anisotropy
۹. Inferring Microstructural Information of White Matter from Diffusion MRI
۱۰. Cross-Subject Comparison of Local Diffusion MRI Parameters
۱۱. Diffusion MRI in Neurological Disorders
۱۲. Diffusion Tensor Imaging in the Study of Aging and Age-Associated Neural Disease
۱۳. Diffusion Imaging in teh Developing Brain
۱۴. Individual Differences in White Matter Microstructure in the Healthy Brain
۱۵. Diffusion Tensor Imaging and its Applications to Schizophrenia and Related Disorders

Section III: Diffusion MRI for In Vivo Neuroanatomy

۱۶. Mapping Connections in Humans and Non-Human Primates: Aspirations and Challenges for Diffusion Imaging
۱۷. Classic and Contemporary Neural Tract-Tracing Techniques
۱۸. The Human Connectome: Linking Structure and Function in the Human Brain
۱۹. MR Diffusion Tractography
۲۰. Validation of Tractography
۲۱. Connectivity Fingerprinting of Gray Matter
۲۲. Contribution of Diffusion Tractography to the Anatomy of Language
۲۳. Presurgical Tractography Applications
۲۴. Comparing Connections in the Brains of Humans and Other Primates Using Diffusion-Weighted Imaging
۲۵. Imaging Structure and Function