This handbook (55 chapters) provides a comprehensive roadmap of basic research in nanomedicine as well as clinical applications. However, unlike other texts in nanomedicine, it not only highlights current advances in diagnostics and therapeutics but also explores related issues like nomenclature, historical developments, regulatory aspects, nanosimilars and 3D nanofabrication. While bridging the gap between basic biomedical research, engineering, medicine and law, the handbook provides a thorough understanding of nano’s potential to address (i) medical problems from both the patient and health provider’s perspective, and (ii) current applications and their potential in a healthcare setting.

Contents

Chapter 1: Science at the Nanoscale:Introduction and Historical Perspective
Chapter 2: Nanomedicine: Dynamic Integration of Nanotechnology with Biomedical Science
Chapter 3: A Small Introduction to the World of Nanomedicine
Chapter 4: Top Ten Recent Nanomedical Research Advances
Chapter 5: The Coming Era of Nanomedicine
Chapter 6: What’s in a Name? Defining Nano in the Context of Drug Delivery
Chapter 7: Properties of Nanoparticulate Materials
Chapter 8: Solid Drug Nanoparticles: Methods for Production and Pharmacokinetic Benefits
Chapter 9: Design and Development of Approved Nanopharmaceutical Products
Chapter 10: Nanosizing Approaches in Drug Delivery
Chapter 11: Multilayered Nanopartides for Personalized Medicine: Translation into Clinical Markets
Chapter 12: Nanomaterials for Pharmaceutical Applications
Chapter 13: Polysaccharides as Nanomaterials for Therapeutics
Chapter 14: The Story of C60 Buckminsterfullerene
Chapter 15: Applications of Nanopartides in Medical Imaging
Chapter 16: Nanoimaging for Nanomedicine
Chapter 17: Nanopartides for Multi-Modality Diagnostic Imaging and Drug Delivery
Chapter 18: Magnetic Nanopartides for Magnetic Resonance Imaging: A Translational Push toward Theranostics
Chapter 19: First-in-Human Molecular Targeting and Cancer Imaging Using Ultrasmall Dual-Modality C Dots
Chapter 20: Atomic Force Microscopy for Nanomedicine
Chapter 21: Atomic Force Microscopy Imaging and Probing of Amyloid Nanoaggregates
Chapter 22: Image-Based High-Content Analysis, Stem Cells and Nanomedicines: A Novel Strategy for Drug Discovery
Chapter 23: Viral Nanopartides: Tools for Materials Science and Biomedicine
Chapter 24: Bacterial Secretion Systems: Nanomachines for Infection and Genetic Diversity
Chapter 25: The Vascular Cartographic Scanning Nanodevice
Chapter 26: Advancements in Ophthalmic Glucose Nanosensors for Diabetes Management
Chapter 27: Towards Nanodiagnostics for Bacterial Infections
Chapter 28: Copaxone® in the Era of Biosimilars and Nanosimilars
Chapter 29: Doxil®: The First FDA-Approved Nanodrug From an Idea to a Product (January 2015 Update)
Chapter 30: Nanotechnology and the Skin Barrier: Topical and Transdermal Nanocarrier-Based Delivery
Chapter 31: Application of Nanotechnology in Non-Invasive Topical Gene Therapy
Chapter 32: Nanocarriers in the Therapy of Inflammatory Disease
Chapter 33: Advanced 3D Nano/Microfabrication Techniques for Tissue and Organ Regeneration
Chapter 34: Nanomedidne for Acute Lung Injury/Acute Respiratory Distress Syndrome: A Shifting Paradigm?
Chapter 35: Nanoviricides: Targeted Anti-Viral Nanomaterials
Chapter 36: Nanotechnology in Tissue Engineering for Orthopaedics
Chapter 37: Applications of Nanomaterials in Dentistry
Chapter 38: Biomimetic Applications in Regenerative Medicine: Scaffolds, Transplantation Modules, Tissue Homing Devices, and Stem Cells
Chapter 39: Potential Applications of Nanotechnology in the Nutraceutical Sector
Chapter 40: Designing Nanocarriers for the Effective Treatment of Cardiovascular Diseases
Chapter 41: Carbon Nanotubes as Substrates for Neuronal Growth
Chapter 42: Polymeric Nanopartides for Cancer Therapeutics
Chapter 43: Nanotechnology for Radiation Oncology
Chapter 44: Gold Nanopartides against Cancer
Chapter 45: Solid Lipid Nanopartides and Nanostructured Lipid Carders for Cancer Therapy
Chapter 46: Nanomedicines Targeted to Aberrant Cancer Signaling and Epigenetics
Chapter 47: Biodegradable Nanopartide-Based Antiretroviral Therapy across the Blood-Brain Barrier
Chapter 48: HIV-Specific Immunotherapy with Synthetic Pathogen-Like Nanopartides
Chapter 49: Biomedical Engineering and Nanoneurosurgery: From the Laboratory to the Operating Room
Chapter 50: Nanotechnology-Based Systems for Microbidde Development
Chapter 51: Nanotechnology-Based Solutions to Combat the Emerging Threat of Superbugs: Current Scenario and Future Prospects
Chapter 52: Nanolithography and Biochips’ Role in Viral Detection
Chapter 53: Lectins as Nano-Tools in Drug Delivery
Chapter 54: Diagnostics of Ebola Hemorrhagic Fever Virus
Chapter 55: Nanomedicine as a Strategy to Fight Thrombotic Diseases