Common factors that lead to treatment failure in head and neck cancer are the lack of tumour oxygenation, the accelerated division of cancer cells during treatment, and radioresistance. These tumour-related challenges and possible ways to overcome them are covered in this book, authored by three medical physicists and a clinical oncologist who explain how different radiobiological findings have led to the development of various treatment techniques for head and neck cancer.

Novel treatment techniques as supported by current scientific evidence are comprehensively explored, as well as the major challenges that arise in the retreatment of patients who have already undergone a form of radiotherapy for primary head and neck cancer.

Features:

• Focuses on and targets specific clinical elements and the radiobiological aspects of head and neck cancer
• Uses an interdisciplinary approach, encompassing clinical aspects of radiotherapy, radiation biology, and medical physics
• Applies content by relating all radiobiological characteristics to their respective clinical implications
• Explains the radiobiological rationale for all previous and current clinical trials for head and neck cancer

Loredana Marcu is Professor of Medical Physics at the University of Oradea, Romania, and Adjunct Professor at School of Health Sciences, University of South Australia. She received her PhD in Medical Physics from the University of Adelaide, and her Masters degree in Applied Physics from the West University of Timisoara, Romania. During her experience in Australia, she coordinated the low dose rate brachytherapy programme at the Royal Adelaide Hospital. She was also a Training Education and Accreditation Program (TEAP) preceptor supervising and coordinating the medical physics training and education of junior physicists in South Australia.