Presents basic concepts, experimental methodology and data acquisition, and processing standards of in vivo NMR spectroscopy

This book covers, in detail, the technical and biophysical aspects of in vivo NMR techniques and includes novel developments in the field such as hyperpolarized NMR, dynamic ^۱۳C NMR, automated shimming, and parallel acquisitions. Most of the techniques are described from an educational point of view, yet it still retains the practical aspects appreciated by experimental NMR spectroscopists. In addition, each chapter concludes with a number of exercises designed to review, and often extend, the presented NMR principles and techniques.

The third edition of In Vivo NMR Spectroscopy: Principles and Techniques has been updated to include experimental detail on the developing area of hyperpolarization; a description of the semi-LASER sequence, which is now a method of choice; updated chemical shift data, including the addition of ^۳۱P data; a troubleshooting section on common problems related to shimming, water suppression, and quantification; recent developments in data acquisition and processing standards; and MatLab scripts on the accompanying website for helping readers calculate radiofrequency pulses.

• Provide an educational explanation and overview of in vivo NMR, while maintaining the practical aspects appreciated by experimental NMR spectroscopists
• Features more experimental methodology than the previous edition
• End-of-chapter exercises that help drive home the principles and techniques and offer a more in-depth exploration of quantitative MR equations
• Designed to be used in conjunction with a teaching course on the subject

In Vivo NMR Spectroscopy: Principles and Techniques, 3^rd Edition is aimed at all those involved in fundamental and/or diagnostic in vivo NMR, ranging from people working in dedicated in vivo NMR institutes, to radiologists in hospitals, researchers in high-resolution NMR and MRI, and in areas such as neurology, physiology, chemistry, and medical biology.

About the Author

Contents

۱ Basic Principles
۲ In Vivo NMR Spectroscopy – Static Aspects
۳ In Vivo NMR Spectroscopy – Dynamic Aspects
۴ Magnetic Resonance Imaging
۵ Radiofrequency Pulses
۶ Single Volume Localization and Water Suppression
۷ Spectroscopic Imaging and Multivolume Localization
۸ Spectral Editing and 2D NMR
۹ Spectral Quantification
۱۰ Hardware
A.1 Matrix Calculations
A.2 Trigonometric Equations
A.3 Fourier Transformation
A.3.1 Introduction
A.3.2 Properties
A.3.2.1 Linearity
A.3.2.2 Time and Frequency Shifting
A.3.2.3 Scaling
A.3.2.4 Convolution
A.3.3 Discrete Fourier Transformation
A.4 Product Operator Formalism
A.4.1 Cartesian Product Operators
A.4.2 Shift (Lowering and Raising) Operators